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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAN3
All Species:
29.7
Human Site:
Y259
Identified Species:
43.56
UniProt:
Q58A45
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58A45
NP_787050.4
741
82181
Y259
V
G
G
T
T
Y
F
Y
T
D
T
T
P
A
P
Chimpanzee
Pan troglodytes
XP_001136622
741
82148
Y259
V
G
G
T
T
Y
F
Y
T
D
T
T
P
A
P
Rhesus Macaque
Macaca mulatta
XP_001097210
741
82134
Y259
V
G
G
T
T
Y
F
Y
T
D
T
T
P
A
P
Dog
Lupus familis
XP_543150
987
105833
Y505
V
G
G
T
T
Y
F
Y
T
D
T
T
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q640Q5
691
76362
A246
N
A
P
S
F
F
M
A
D
E
L
R
Q
E
L
Rat
Rattus norvegicus
XP_002724835
883
95283
Y401
V
G
G
T
T
Y
F
Y
T
D
T
T
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519591
717
78728
A263
P
P
T
A
P
H
V
A
Y
M
Q
P
K
A
N
Chicken
Gallus gallus
XP_417120
757
83269
Y276
V
G
G
T
T
Y
F
Y
T
D
T
T
P
A
P
Frog
Xenopus laevis
NP_001128699
631
68072
K186
L
T
M
S
Q
R
R
K
A
P
N
P
T
A
N
Zebra Danio
Brachydanio rerio
XP_002666687
799
86684
Y318
V
G
G
T
T
Y
F
Y
T
D
N
T
P
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728797
788
85176
T263
P
I
P
S
A
L
P
T
S
V
H
Q
E
N
V
Honey Bee
Apis mellifera
XP_623553
607
67474
V162
Q
A
A
L
S
F
F
V
S
E
S
L
R
M
D
Nematode Worm
Caenorhab. elegans
P34653
632
71182
S187
Y
N
A
P
L
P
I
S
H
M
A
R
F
R
G
Sea Urchin
Strong. purpuratus
XP_796055
760
83393
P278
F
Y
T
D
D
Q
G
P
A
V
P
Q
A
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36102
679
76436
Y234
S
L
L
Q
Y
H
L
Y
A
P
E
Q
P
S
S
Red Bread Mold
Neurospora crassa
Q7SDP4
656
73993
Y211
H
P
P
N
Y
H
L
Y
Q
P
P
S
E
L
Y
Conservation
Percent
Protein Identity:
100
99.8
99.7
74.4
N.A.
90.1
82.2
N.A.
80.8
78.3
58.4
68.2
N.A.
38.5
41.8
31.9
49.3
Protein Similarity:
100
100
99.8
74.7
N.A.
90.9
83
N.A.
86
84.1
64
75
N.A.
55.7
59.6
49.5
62.6
P-Site Identity:
100
100
100
100
N.A.
0
100
N.A.
6.6
100
6.6
93.3
N.A.
0
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
13.3
100
20
93.3
N.A.
13.3
40
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
45.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
7
7
0
0
13
19
0
7
0
7
57
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
7
44
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
13
7
0
13
7
0
% E
% Phe:
7
0
0
0
7
13
50
0
0
0
0
0
7
0
0
% F
% Gly:
0
44
44
0
0
0
7
0
0
0
0
0
0
0
7
% G
% His:
7
0
0
0
0
19
0
0
7
0
7
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% K
% Leu:
7
7
7
7
7
7
13
0
0
0
7
7
0
7
7
% L
% Met:
0
0
7
0
0
0
7
0
0
13
0
0
0
7
0
% M
% Asn:
7
7
0
7
0
0
0
0
0
0
13
0
0
7
13
% N
% Pro:
13
13
19
7
7
7
7
7
0
19
13
13
50
7
44
% P
% Gln:
7
0
0
7
7
7
0
0
7
0
7
19
7
0
0
% Q
% Arg:
0
0
0
0
0
7
7
0
0
0
0
13
7
7
0
% R
% Ser:
7
0
0
19
7
0
0
7
13
0
7
7
0
7
7
% S
% Thr:
0
7
13
44
44
0
0
7
44
0
38
44
7
0
0
% T
% Val:
44
0
0
0
0
0
7
7
0
13
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
13
44
0
57
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _